Leipzig:: Hirzel,, 1865..
Ludwig, Carl Friedrich Wilhelm (1816-95). Die physiologischen Leistungen des Blutdrucks. 8vo. 24pp. Leipzig: Hirzel, 1865. 232 x 150 mm. Original green printed wrappers, repaired; in quarter morocco box. Light browning, otherwise fine.
First Edition. Garrison-Morton 778: "Ludwig's inaugural address at Leipzig, in which he introduced the idea of keeping alive excised portions of organs by means of artificial circulation, or perfusion. He suggested that the blood-pressure had a stimulating effect on the vagus." This was a significant step toward the eventual development of organ transplantation and heart surgery.
As the first professor of physiology at the University of Leipzig, Ludwig created a model physiological institute where he studied vital phenomena in terms of the laws of physics and chemistry. "Ludwig hoped to elucidate physiological problems by combining the study of the anatomy of an organ with a knowledge of the physicochemical changes that occur in its functioning. . . . Ludwig's combination of ingenuity, resourcefulness and knowledge of physical science enabled him to become one of the greatest experimenters in the history of physiology" (DSB).